The Pacific lineage (2E) of JC polyomavirus is prevalent in Sumba Island, Eastern Indonesia
نویسندگان
چکیده
Recent studies have identified a Pacific lineage (2E) of JC polyomavirus (also designated as JC virus or JCV) that occurs in both Island Southeast Asia and Oceania, but not in mainland Asia. It has been postulated that this lineage traveled with Austronesian-speaking people who are now spread throughout Island Southeast Asia and Oceania (excluding Australia and inland and southern New Guinea). However, to date, the 2E lineage has been identified in Southeast Asia only in populations of the Philippine islands. Here we report that a high incidence of the 2E lineage was detected in the people of Sumba Island, eastern Indonesia.
منابع مشابه
Polyomavirus-Associated Progressive Multifocal Leukoencephalopathy (PML) in HAART era
Polyomaviruses may cause human disease, particularly in immunocompromised hosts. JCV, one of the members of polyomaviridae family, is the causative agent of the neurological disease progressive multifocal leukoencephalopathy (PML), which occurs mostly in immunocompromised patients. Progressive Multifocal leukoencephalopathy (PML) is a progressive demyelinating disorder of the central nervous sy...
متن کاملGood efficacy of artemether-lumefantrine for uncomplicated falciparum malaria in eastern Sumba, East Nusatenggara, Indonesia.
AIM to evaluate the safety and efficacy of a fixed combination of artemether-lumefantrine for likely use against failures of the artesunate-amodiaquine first line therapy. METHODS the study was an open label single arm uncontrolled trial. we evaluated the safety and efficacy of standard artemether-lumefantrine therapy in 59 subjects with uncomplicated malaria caused by Plasmodium falciparum o...
متن کاملG6PD Deficiency at Sumba in Eastern Indonesia Is Prevalent, Diverse and Severe: Implications for Primaquine Therapy against Relapsing Vivax Malaria
Safe treatment of Plasmodium vivax requires diagnosis of both the infection and status of erythrocytic glucose-6-phosphate dehydrogenase (G6PD) activity because hypnozoitocidal therapy against relapse requires primaquine, which causes a mild to severe acute hemolytic anemia in G6PD deficient patients. Many national malaria control programs recommend primaquine therapy without G6PD screening but...
متن کاملCoevolution of languages and genes on the island of Sumba, eastern Indonesia.
Numerous studies indicate strong associations between languages and genes among human populations at the global scale, but all broader scale genetic and linguistic patterns must arise from processes originating at the community level. We examine linguistic and genetic variation in a contact zone on the eastern Indonesian island of Sumba, where Neolithic Austronesian farming communities settled ...
متن کاملHeavy burden of intestinal parasite infections in Kalena Rongo village, a rural area in South West Sumba, eastern part of Indonesia: a cross sectional study
BACKGROUND Intestinal parasitic infections (IPIs) are one of the major public health problems, especially in the rural area of developing countries with low socio-economic status and poor sanitation. The study was aimed to determine the prevalence of IPIs among the inhabitants of a rural area in South West Sumba, eastern part of Indonesia. METHODS A cross-sectional study was done in Kalena Ro...
متن کامل